Track 01 of 9
Synthetic Biology & Biomanufacturing
Cell-free systems, metabolic engineering and industrial biotech.
Synthetic biology has matured from artisanal pathway construction into a design-build-test-learn discipline backed by AI-guided enzyme engineering and high-throughput strain screening. GSBG 2027 will examine cell-free protein synthesis platforms (Sutro, Nuclera), Ginkgo Bioworks-style automated foundries, and the use of generative models like ESM3 and ProGen to design novel biosynthetic enzymes. Sessions will cover continuous biomanufacturing, perfusion bioreactor scale-up for mRNA and AAV production, and the rapid expansion of precision fermentation for recombinant proteins, alternative proteins, and cultivated meat.
Focus areas
- Cell-free protein synthesis: Sutro XpressCF, Nuclera eProtein
- AI-guided enzyme design: ESM3, ProGen, RFdiffusion for biocatalysts
- Automated strain engineering foundries and DBTL cycles
- Perfusion bioreactors and continuous biomanufacturing
- Precision fermentation: recombinant proteins and cultivated meat
- CHO and HEK293 cell line development for biologics
- mRNA and AAV manufacturing scale-up and analytics